SODIUM LAURYL SULFATE

*SYNONYMS:
SULFURIC ACID, MONODODECYL ESTER, SODIUM SALT
DODECYL ALCOHOL, HYDROGEN SULFATE, SODIUM SALT
DODECYL SODIUM SULFATE
DODECYL SULFATE SODIUM
LAURYL SODIUM SULFATE
SODIUM LAURYL SULFATE
AKYPOSAL SDS
AQUAREX ME
AQUAREX METHYL
AVIROL 101
AVIROL 118 CONC
BEROL 452
CARSONOL SLS
CARSONOL SLS PASTE B
CARSONOL SLS SPECIAL
CONCO SULFATE WA
CONCO SULFATE WA-1200
CONCO SULFATE WA-1245
CONCO SULFATE WAG
CONCO SULFATE WAN
CONCO SULFATE WAS
CONCO SULFATE WN
CYCLORYL 21
CYCLORYL 31
CYCLORYL 580
CYCLORYL 585N
DEHAG SULFATE GL EMULSION
DEHAG SULPHATE GL EMULSION
DETERGENT 66
N-DODECYL SULFATE SODIUM
DODECYL SULFATE, SODIUM SALT
DREFT
DUPONAL WAQE
DUPANAL
DUPONOL
DUPONOL C
DUPONOL ME
DUPONOL METHYL
DUPONOL QX
DUPONOL WA
DUPONOL WA DRY
DUPONOL WAQ
DUPONOL WAQA
DUPONOL WAQE
DUPONOL WAQM
EMAL O
EMAL 10
EMERSAL 6400
EMPICOL LPZ
EMPICOL LS 30
EMPICOL LX 28
EMULSIFIER NO. 104
FINASOL OSR (SUB 2)
GARDINOL
HEXAMOL SLS
IRIUM
LANETTE WAX-S
LAURYL SULFATE, SODIUM SALT
MAPROFIX 563
MAPROFIX LK
MAPROFIX NEU
MAPROFIX WAC
MAPROFIX WAC-LA
MELANOL CL
MELANOL CL 30
MONODODECYL SODIUM SULFATE
MONOGEN Y 100
MONTOPOL LA PASTE
NCI-C50191
NEUTRAZYME
NIKKOL SLS
ODORIPON AL 95
ORVUS WA PASTE
P AND G EMULSIFIER 104
PERLANDROL L
PRODUCT NO. 75
PRODUCT NO. 161
QUOLAC EX-UB
REWOPOL NLS 30
RICHONOL A
RICHONOL AF
RICHONOL C
SINNOPON LS 95
SINNOPON LS 100
SINTAPON L
SIPEX OP
SIPEX SB
SIPEX SD
SIPEX SP
SIPEX UB
SIPON LS
SIPON LS 100
SIPON LSB
SIPON PD
SIPON WD
SLS
SODIUM DOCECYL SULFATE
SODIUM N-DODECYL SULFATE
SODIUM DODECYL SULPHATE
SODIUM LAURYL SULPHATE
SODIUM MONODODECYL SULFATE
SODIUM MONOLAURYL SULFATE
SOLSOL NEEDLES
STANDAPOL 112 CONC
STEINAPOL NLS 90
STEPANOL ME
STERLING WA PASTE
SULFETAL L 95
SULFOPON WA 1
SULFOTEX WA
SWASCOL 3L
SYNTAPON
TARAPON K 12
TEXAPON DL CONC.
TREPENOL WA
TVM 474
ULTRA SULFATE SL-1
WAQE

-PHYSICAL CHEMICAL DATA
======================

*PHYSICAL DESCRIPTION: LITERATURE: White to cream-colored crystals, flakes or
powder
REPOSITORY: White powder

*MOLECULAR WEIGHT: 288.38

*SPECIFIC GRAVITY: Not available

*DENSITY: Not available

*MP (DEG C): 204-207 C [055,269]

*BP (DEG C): Not available

*SOLUBILITIES:
WATER : <1 mg/mL @ 19 C (RAD)

DMSO : 10-50 mg/mL @ 19 C (RAD)

95% ETHANOL : <1 mg/mL @ 19 C (RAD)

METHANOL : 5-10 mg/mL @ 17 C (RAD)

ACETONE : <1 mg/mL @ 19 C (RAD)

TOLUENE : <1 mg/mL @ 17 C (RAD)

OTHER SOLVENTS:
Alcohol: Partly soluble [295]
Chloroform: Practically insoluble [295]
Ether: Practically insoluble [295]
Light petroleum: Practically insoluble [295]

*VOLATILITY:
Vapor pressure: Not available
Vapor density : Not available

*FLAMMABILITY(FLASH POINT):
Flash point data for this chemical are not available; however, it is
probably combustible. Fires involving this material can be controlled with
a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also
be used [058].

*UEL: Not available LEL: Not available

*REACTIVITY:
This chemical has neutral reactions [031,051]. It is incompatible
with strong oxidizers [058,269]. It is also incompatible with cationic
materials and with acids with pH below 2.5 [295].

*STABILITY:
This chemical is stable under normal laboratory conditions [058].
Solutions of this chemical in water, DMSO, 95% ethanol or acetone should
be stable for 24 hours under normal lab conditions (RAD).

*OTHER PHYSICAL DATA:
Melting point also reported as 184-185 C [052]
Endotherms occur @ 60 C, 81-88 C, 204 C, 211 C and 226 C [052]
log P octanol: 1.60 [055]
Smooth feel [031,051]
Forms an opalescent solution in water [031,051,062]
Lowers the surface tension of aqueous solutions [031,051]
Emulsifies fats [031,051]
Faint odor of fatty substances [031,051,058]

-TOXICITY
========

*NIOSH REGISTRY NUMBER: WT1050000

*TOXICITY: (abbreviations)
        typ. dose    mode     specie      amount     units     other
          LD50       orl       rat         1288      mg/kg
          LD50       ipr       rat          210      mg/kg
          LD50       ivn       rat          118      mg/kg
          LD50       ipr       mus          250      mg/kg
          LD50       ivn       mus          118      mg/kg

*AQTX/TLM96: Not available

*SAX TOXICITY EVALUATION:
THR: Poison by intravenous and intraperitoneal routes. Moderately toxic
       by ingestion. An experimental teratogen. Experimental reproductive
       effects. A human skin irritant. An experimental eye and severe skin
       irritant. A mild allergen. Mutagenic data.

*CARCINOGENICITY: Not available

*MUTATION DATA:
       test          lowest dose      |      test          lowest dose
    -----------   -----------------   |   -----------   -----------------
    mmo-omi          200 mg/L         |   mmo-smc         3500 umol/L
    sln-asn          900 ppm          |   dni-gpg:kdy       60 umol/L

*TERATOGENICITY:
Reproductive Effects Data:
TDLo: skn-mus 480 mg/kg (6-13D preg)

*STANDARDS, REGULATIONS & RECOMMENDATIONS:
OSHA: None
ACGIH: None
NIOSH Criteria Document: None
NFPA Hazard Rating: Health (H): None
Flammability (F): None
Reactivity (R): None

*OTHER TOXICITY DATA:
Skin and Eye Irritation Data:
    skn-hmn   250 mg/24H MLD
    skn-hmn    25 mg/24H MLD
    skn-dog    25 mg/24H MLD
    skn-rbt    25 mg/24H MOD
    skn-rbt   250 mg/24H MOD
    skn-rbt    10 mg/24H
    skn-rbt    50 mg/24H MLD
    eye-rbt     2 mg
    skn-pig    25 mg/24H MLD
    skn-gpg    25 mg/24H MLD
    skn-mus    25 mg/24H MOD
    skn-rbt    50 mg/24H SEV
    eye-rbt   100 mg/24H MOD
    eye-rbt    10 mg MOD
    eye-rbt   250 ug MLD
Review: Toxicology Review
Status: EPA TSCA Chemical Inventory, 1986
          EPA TSCA Test Submission (TSCATS) Data Base, June 1989
          Meets criteria for proposed OSHA Medical Records Rule

-OTHER DATA (Regulatory)
=======================

*PROPER SHIPPING NAME (IATA): Other regulated substances

*UN/ID NUMBER: ID8027

*HAZARD CLASS: 9 SUBSIDIARY RISK: None PACKING GROUP: None

*LABELS REQUIRED: Miscellaneous

*PACKAGING: PASSENGER: PKG. INSTR.: 906 MAXIMUM QUANTITY: No
limit
CARGO : PKG. INSTR.: 906 MAXIMUM QUANTITY: No limit

*SPECIAL PROVISIONS: None

*USES:
This compound is used as a wetting agent in textiles, as a detergent
(sometimes in toothpastes), as a food additive, as a surfactant, as an
emulsifier and as a thickener. It can be used in hard water.

*COMMENTS: Not available

-HANDLING PROCEDURES
===================

*ACUTE/CHRONIC HAZARDS:
This comopund is an irritant of the skin, eyes and respiratory tract
[058,099,295]. When heated to decomposition it emits toxic fumes of carbon
monoxide, carbon monoxide, hydrogen sulfide and sulfur oxides [043,058,269].

*MINIMUM PROTECTIVE CLOTHING: Not available

*RECOMMENDED GLOVE MATERIALS:
GlovES+ Expert System Glove Types For The Neat (Undiluted) Chemical:
This chemical has not been tested for permeation by Radian Corporation;
however, the GlovES+ expert system was used to extrapolate permeation test
information from compounds in the same chemical class. The GlovES+ system uses
permeation data from literature sources; therefore, extra safety margins should
be used with the estimated protection time(s). If this chemical makes direct
contact with your glove, or if a tear, puncture or hole develops, replace them
at once.
The GlovES+ expert system is a tool that can help people better manage
protection from chemicals, however this tool cannot replace sound judgment nor
make technical decisions. Our GlovES+ expert system is designed to offer
initial advice and assistance in glove selection while the final glove
selection should be made by knowledgeable individuals based on the specific
circumstances involved.

Glove Type            Model Number      Thickness   Estimated Protection Time
Butyl rubber          North B-174        0.68 mm            480 min
Nitrile               Edmont 37-155      0.35 mm            480 min
Neoprene              Edmont 29-840      0.28 mm            480 min
PVC                   Edmont 34-100      0.14 mm            240 min

*RECOMMENDED RESPIRATOR:
Where the neat test chemical is weighed and diluted, wear a NIOSH-
approved half face respirator equipped with an organic vapor/acid gas
cartridge (specific for organic vapors, HCl, acid gas and SO2) with a
dust/mist filter.

*OTHER: Not available

*STORAGE PRECAUTIONS:
You should store this chemical under ambient temperatures,
and keep it away from oxidizing materials.

*SPILLS AND LEAKAGE:
If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. You
should then dampen the solid spill material with 60-70% methanol, then transfer
the dampened material to a suitable container. Use absorbent paper dampened
with methanol to pick up any remaining material. Your contaminated clothing
and absorbent paper should be sealed in a vapor-tight plastic bag for eventual
disposal. Solvent-wash contaminated surfaces with 60-70% methanol followed by
washing with a soap and water solution. Do not reenter the contaminated area
until the Safety Officer (or other responsible person) has verified that the
area has been properly cleaned.

*DISPOSAL AND WASTE TREATMENT: Not available

-EMERGENCY PROCEDURES
====================

*SKIN CONTACT:
IMMEDIATELY flood affected skin with water while removing and isolating
all contaminated clothing. Gently wash all affected skin areas thoroughly
with soap and water.
If symptoms such as redness or irritation develop, IMMEDIATELY call a
physician and be prepared to transport the victim to a hospital for treatment.

*INHALATION:
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air.
If symptoms (such as wheezing, coughing, shortness of breath, or burning in
the mouth, throat, or chest) develop, call a physician and be prepared to
transport the victim to a hospital.
Provide proper respiratory protection to rescuers entering an unknown
atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA)
should be used; if not available, use a level of protection greater than or
equal to that advised under Respirator Recommendation.

*EYE CONTACT:
      First check the victim for contact lenses and remove if present. Flush
victim's eyes with water or normal saline solution for 20 to 30 minutes while
simultaneously calling a hospital or poison control center.
      Do not put any ointments, oils, or medication in the victim's eyes without
specific instructions from a physician.
      IMMEDIATELY transport the victim after flushing eyes to a hospital even if
no symptoms (such as redness or irritation) develop.

*INGESTION:
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing,
give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a
hospital or poison control center. Be prepared to transport the victim to a
hospital if advised by a physician.
If the victim is convulsing or unconscious, do not give anything by mouth,
ensure that the victim's airway is open and lay the victim on his/her side with
the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY
transport
the victim to a hospital.

*SYMPTOMS:
Symptoms of exposure to this compound include irritation of the skin
with rash, irritation of the eyes with redness and pain, irritation of the
nose, throat and respiratory tract, gastrointestinal distress, nausea,
diarrhea, sore throat, coughing and choking [058]. It may also cause mild
skin allergies [051].

-SOURCES
=======

*SOURCES:
[015] Lewis, R.J., Sr. and R.L. Tatken, Eds. Registry of Toxic Effects
          of Chemical Substances. On-line Ed. National Institute for
          Occupational Safety and Health. Cincinnati, OH. WT1050000.
          December 4, 1989.

[031] Windholz, M., Ed. The Merck Index. 10th Ed. Merck and Co.
Rahway, NJ. 1983. p. 1237, #8474.

[043] Sax, N.I. and Richard J. Lewis, Sr. Dangerous Properties of Industrial
Materials. 7th Ed. Van Nostrand Reinhold. New York. 1989.
Vol. III, p. 3150, #SDN500.

[051] Sax, N. Irving, Ed. Dangerous Properties of Industrial Materials
Report. Bi-monthly Updates. Van Nostrand Reinhold Company, Inc.
New York. January/February 1982. Vol. 2, No. 1, p. 117.

[052] Midwest Research Institute. MRI Report for Sodium dodecyl sulfate.
Kansas City, MO. May 12, 1975.

[055] Verschueren, K. Handbook of Environmental Data on Organic
Chemicals. 2nd Ed. Van Nostrand Reinhold. New York. 1983.
p. 793.

[058] Information Handling Services. Material Safety Data Sheets
Service. Microfiche Ed. Bimonthly Updates. December 1989/
January 1990. #5846-076, A-01.

[062] Sax, N.I. and R.J. Lewis Sr., Eds. Hawley's Condensed Chemical
Dictionary. 11th Ed. Van Nostrand Reinhold. New York. 1987.
p. 1064.

[082] U.S. Environmental Protection Agency, Office of Toxic Substances.
          Toxic Substances Control Act Chemical Substance Inventory: 1985
          Edition. 5 Vols. U.S. Environmental Protection Agency.
          Washington, D.C. January 1986. Listed.

[099] Grant, W. Morton, M.D. Toxicology of the Eye. 3rd Ed. Charles
C. Thomas, Publisher. Springfield, IL. 1986. p. 871.

[110] Oak Ridge National Laboratory. Environmental Mutagen Information
Center (EMIC), Bibliographic Data Base. Oak Ridge National
Laboratory. Oak Ridge, TN. Listed.

[120] Oak Ridge National Laboratory. Environmental Teratogen Information
Center (ETIC), Bibliographic Data Base. Oak Ridge National
Laboratory. Oak Ridge, TN. Not listed.

[151] Gosselin, R.E., H.C. Hodge, and R.P. Smith. Clinical Toxicology
of Commercial Products. 5th Ed. Williams and Wilkins, Co.
Baltimore. 1984. p. II-274, #946.

[195] Estrin, F.E., P.A. Crosley and C.R. Haynes, Eds. CFTA Cosmetic
Ingredient Dictionary. 3rd Ed. The Cosmetic, Toiletry and
Fragrance Assn. Inc. Washington. 1982. p. 285.

[269] Lenga, Robert E. The Sigma-Aldrich Library of Chemical Safety Data.
Edition 1. Sigma-Aldrich Corporation. Milwaukee, WI. 1985.
p. 847, #C.

[275] Aldrich Chemical Company. Aldrich Catalog/Handbook of Fine
Chemical. Aldrich Chemical Co., Inc. Milwaukee, WI.
1988. p. 662, #85,192-2.

[295] Reynolds, James E.F., Ed. Martindale The Extra Pharmacopoeia. 28th Ed.
The Pharmaceutical Press. London. 1982. p. 1442.

[406] Goodman, L.S., A. Gilman, F. Murad and T.W. Rall, Eds. The
Pharmacological Basis of Therapeutics. 7th Ed. Macmillan
Publishing Co. New York. 1985. p. 947.

[610] Clansky, Kenneth B., Ed. Suspect Chemicals Sourcebook: A Guide to
          Industrial Chemicals Covered Under Major Federal Regulatory and
          Advisory Programs. Roytech Publications, Inc. Burlingame, CA.
          1990. Section 3, p. 60.

[620] United States National Toxicology Program. Chemical Status Report.
NTP Chemtrack System. Research Triangle Park, NC. November 6, 1990.
Listed.